CSIR NET Life Science Unit 3 MCQs with Answers

Here below are 15 core Cell Communication and Cell Signaling topics across five parts. Choose Easy, Medium or Difficult for each topic to practise 15 questions per level. Answers show the correct option and explanation immediately.

Part 1Part 2Part 3Part 4Part 5

Part 1: Topics 1–3

1. Receptors and Modes of Cell Signaling

15 questions per difficulty level · Select a level to start

2. G Protein-Coupled Receptors

15 questions per difficulty level · Select a level to start

3. Second Messengers and Signal Amplification

15 questions per difficulty level · Select a level to start

Part 2: Topics 4–6

4. Receptor Tyrosine Kinases

15 questions per difficulty level · Select a level to start

5. MAPK and Ras Signaling

15 questions per difficulty level · Select a level to start

6. PI3K-Akt-mTOR Signaling

15 questions per difficulty level · Select a level to start

Part 3: Topics 7–9

7. JAK-STAT Signaling

15 questions per difficulty level · Select a level to start

8. TGF-beta and SMAD Signaling

15 questions per difficulty level · Select a level to start

9. Wnt and Beta-Catenin Signaling

15 questions per difficulty level · Select a level to start

Part 4: Topics 10–12

10. Notch and Hedgehog Signaling

15 questions per difficulty level · Select a level to start

11. Cell Adhesion and Integrin Signaling

15 questions per difficulty level · Select a level to start

12. Cell Cycle Signaling and Growth Factors

15 questions per difficulty level · Select a level to start

Part 5: Topics 13–15

13. Apoptosis and Survival Signaling

15 questions per difficulty level · Select a level to start

14. Immune Cell Signaling

15 questions per difficulty level · Select a level to start

15. Signal Integration, Feedback and Experimental Methods

15 questions per difficulty level · Select a level to start

Frequently Asked Questions

How do GPCRs transmit extracellular signals?

Ligand binding changes receptor conformation and promotes activation of associated heterotrimeric G proteins.

What is the role of cAMP in cell signaling?

cAMP acts as a second messenger and commonly activates protein kinase A.

How does an RTK become activated?

Ligand binding often promotes receptor dimerization or rearrangement and tyrosine autophosphorylation.

What distinguishes apoptosis from necrotic cell death?

Apoptosis is a regulated cell-death program with characteristic caspase activity; necrotic death commonly involves loss of membrane integrity.

Why are feedback loops important in signaling pathways?

Negative feedback can dampen or terminate signaling, while positive feedback can amplify or stabilize a response.

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